Open AccessSodium butyrate attenuates high-fat diet-induced steatohepatitis in mice by improving gut microbiota and gastrointestinal barrier
Author(s) -
Detang Zhou,
Qin Pan,
FengZhi Xin,
Rui-Nan Zhang,
Chong-Xin He,
Guangyu Chen,
Chang Liu,
Yuanwen Chen,
JianGao Fan
Publication year - 2017
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v23.i1.60
Subject(s) - gut flora , sodium butyrate , medicine , steatohepatitis , butyrate , fatty liver , endocrinology , inflammation , biology , liver injury , immunology , biochemistry , disease , fermentation , gene
To investigate whether gut microbiota metabolite sodium butyrate (NaB) is an effective substance for attenuating non-alcoholic fatty liver disease (NAFLD) and the internal mechanisms.