Open AccessKlebsiella pneumoniaeinvasive liver abscess syndrome with purulent meningitis and septic shock: A case from mainland China
Author(s) -
Yun Qian,
Chi-Chun Wong,
Shih-Kung Lai,
Zhenghua Lin,
Wei Zheng,
Hui Zhao,
Kong-Han Pan,
Shujie Chen,
Jianmin Si
Publication year - 2016
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v22.i9.2861
Subject(s) - medicine , septic shock , liver abscess , klebsiella pneumoniae , meningitis , abscess , brain abscess , hydrocephalus , surgery , sepsis , biology , biochemistry , escherichia coli , gene
We present a rare case of invasive liver abscess syndrome due to Klebsiella pneumoniae (K. pneumoniae) with metastatic meningitis and septic shock. A previously healthy, 55-year-old female patient developed fever, liver abscess, septic shock, purulent meningitis and metastatic hydrocephalus. Upon admission, the clinical manifestations, laboratory and imaging examinations were compatible with a diagnosis of K. pneumoniae primary liver abscess. Her distal metastasis infection involved meningitis and hydrocephalus, which could flare abruptly and be life threatening. Even with early adequate drainage and antibiotic therapy, the patient's condition deteriorated and she ultimately died. To the best of our knowledge, this is the first case of K. pneumoniae invasive liver abscess syndrome with septic meningitis reported in mainland China. Our findings reflect the need for a better understanding of the epidemiology, risk factors, complications, comorbid medical conditions and treatment of this disease.