Open AccessGlucose deprivation induces chemoresistance in colorectal cancer cells by increasing ATF4 expression
Author(s) -
Yaling Hu,
Yuan Yin,
He-Yong Liu,
Yuyang Feng,
Zehua Bian,
Leyuan Zhou,
Jiwei Zhang,
Bojian Fei,
Yugang Wang,
Zhaohui Huang
Publication year - 2016
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v22.i27.6235
Subject(s) - atf4 , apoptosis , cancer research , colorectal cancer , oxaliplatin , western blot , unfolded protein response , biology , microbiology and biotechnology , cancer , medicine , gene , biochemistry
To investigate the role of activating transcription factor 4 (ATF4) in glucose deprivation (GD) induced colorectal cancer (CRC) drug resistance and the mechanism involved.