Open AccessWortmannin influences hypoxia-inducible factor-1 alpha expression and glycolysis in esophageal carcinoma cells
Author(s) -
Ling Zeng,
Hai-Yun Zhou,
Nana Tang,
Weifeng Zhang,
Guijun He,
Hao Bo,
Yadong Feng,
Hong Zhu
Publication year - 2016
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v22.i20.4868
Subject(s) - glycolysis , wortmannin , protein kinase b , pi3k/akt/mtor pathway , biology , cancer research , biochemistry , signal transduction , metabolism
To investigate the influence of phosphatidylinositol-3-kinase protein kinase B (PI3K/AKT)-HIF-1α signaling pathway on glycolysis in esophageal carcinoma cells under hypoxia.