Open AccessRole of estrogen receptor β selective agonist in ameliorating portal hypertension in rats with CCl4-induced liver cirrhosis
Author(s) -
Chenggang Zhang,
Bin Zhang,
Wensheng Deng,
Manlin Duan,
Wei Chen,
Zijian Wu
Publication year - 2016
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v22.i18.4484
Subject(s) - endocrinology , medicine , hepatic stellate cell , rhoa , agonist , portal venous pressure , portal hypertension , chemistry , masson's trichrome stain , estrogen receptor , cirrhosis , hepatic fibrosis , enos , in vivo , fibrosis , nitric oxide , nitric oxide synthase , biology , receptor , signal transduction , biochemistry , cancer , breast cancer , microbiology and biotechnology
To investigate the role of diarylpropionitrile (DPN), a selective agonist of estrogen receptor β (ERβ), in liver cirrhosis with portal hypertension (PHT) and isolated hepatic stellate cells (HSCs).