Open AccessLiuweiwuling tablets protect against acetaminophen hepatotoxicity: What is the protective mechanism?
Author(s) -
Kuo Du,
Hartmut Jaeschke
Publication year - 2016
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v22.i11.3302
Subject(s) - acetaminophen , pharmacology , medicine , liver injury , mechanism (biology) , liver damage , traditional medicine , philosophy , epistemology
Study of the effects of natural products, including traditional Chinese Medicines, on acetaminophen hepatotoxicity has gained considerable popularity in recent years, and some of them showed positive results and even promising therapeutic potentials. A recent report suggested that Liuweiwuling tablets protect against acetaminophen hepatotoxicity and promote liver regeneration in a rodent model through alleviating the inflammatory response. However, several concerns exist regarding the limitations of the experimental design and interpretation of the data presented in this manuscript.