Open AccessSynergistic anticancer properties of docosahexaenoic acid and 5-fluorouracil through interference with energy metabolism and cell cycle arrest in human gastric cancer cell line AGS cells
Author(s) -
Kun Gao,
Qi Liang,
Zhihao Zhao,
You-Fen Li,
Shufeng Wang
Publication year - 2016
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v22.i10.2971
Subject(s) - cell cycle , docosahexaenoic acid , cell growth , cell cycle checkpoint , cell culture , cell , flow cytometry , mtt assay , apoptosis , chemistry , cancer cell , microbiology and biotechnology , pharmacology , cancer , biochemistry , biology , medicine , fatty acid , polyunsaturated fatty acid , genetics
To explore the synergistic effect of docosahexaenoic acid (DHA)/5-fluorouracil (5-FU) on the human gastric cancer cell line AGS and examine the underlying mechanism.