Open AccessNatural YMDD-motif mutants affect clinical course of lamivudine in chronic hepatitis B
Author(s) -
Youwen Tan,
Yun Ye,
Ge Gao,
Wei Zhao,
Jing Gan,
Yun Zhao,
Zhi-Lin Niu,
Dongjun Zhang,
Li Chen,
Xianjun Yu,
Liying Yang
Publication year - 2015
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v21.i7.2089
Subject(s) - lamivudine , medicine , virology , aspartic acid , hepatitis b , hepatitis b virus , methionine , gastroenterology , virus , amino acid , biology , genetics
To investigate the prevalence of nature tyrosine-methionine-aspartic acid-aspartic acid motif mutations in chronic hepatitis B (CHB) patients and to evaluate the efficacy of lamivudine.