Open AccessDepletion of theIKBKAPortholog in zebrafish leads to hirschsprung disease-like phenotype
Author(s) -
William Cheng,
Clara S. Tang,
Hongsheng Gui,
Man-Ting So,
Vincent Chi-Hang Lui,
Paul KwongHang Tam,
María-Mercé García-Barceló
Publication year - 2015
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v21.i7.2040
Subject(s) - morpholino , biology , microbiology and biotechnology , zebrafish , genetics , gene
To investigate the role of IKBKAP (inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein) in the development of enteric nervous system (ENS) and Hirschsprung disease (HSCR).