Open AccessRapidly aggravated skeletal muscle metastases from an intrahepatic cholangiocarcinoma
Author(s) -
Jiyoung Lee
Publication year - 2015
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v21.i6.1989
Subject(s) - medicine , intrahepatic cholangiocarcinoma , magnetic resonance imaging , radiology , metastasis , biopsy , chemotherapy , adenocarcinoma , radiation therapy , magnetic resonance cholangiopancreatography , palliative care , iliopsoas muscle , surgery , endoscopic retrograde cholangiopancreatography , pathology , abscess , cancer , nursing , pancreatitis
We present a rare case of intrahepatic cholangiocarcinoma (ICC) with multiple skeletal muscle metastases. The patient was a 55-year-old Asian woman presenting with abdominal pain; abdominal and pelvic computed tomography and magnetic resonance cholangiopancreatography revealed an unresectable ICC with hepatic metastasis and metastastatic lymphadenopathy in the porto-caval area. After 3 mo of treatment with palliative radiotherapy and chemotherapy, magnetic resonance imaging of the thoracolumbar spine detected right psoas muscle and paraspinous muscle metastases. We performed an ultrasound-guided percutaneous fine-needle biopsy that confirmed a similar pattern of poorly differentiated adenocarcinoma. The patient treated with palliative chemotherapy and achieved 10 mo of survival. Here we report the first case quickly spread to multiple sites of muscle even though the three-month treatment, compare to the other cases reported muscle metastases at diagnosis.