Open AccessGastric metastasis from small cell lung cancer: A case report
Author(s) -
Song Gao,
Xudong Hu,
Shuzhen Wang,
Ning Liu,
Wei Zhao,
Qingxi Yu,
Wei Hou,
Shuanghu Yuan
Publication year - 2015
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v21.i5.1684
Subject(s) - medicine , cytokeratin , metastasis , synaptophysin , pathology , stomach , cancer , small cell carcinoma , immunohistochemistry , lung , adenocarcinoma , bone metastasis , lung cancer , neuroendocrine tumors , biopsy
Small cell lung cancer (SCLC) represents a group of highly malignant tumors that give rise to early and widespread metastases at the time of diagnosis. The preferential metastatic sites are the brain, liver, adrenal glands, bone, and bone marrow. However, metastases of the gastrointestinal system, especially the stomach, are rare; most cases of stomach metastasis are asymptomatic and, as a result, are usually only discovered at autopsy. We report a case of gastric metastasis originating from SCLC. The patient was a 66-year-old man admitted to our hospital due to abdominal pain. He underwent gastroscopy, with the pathological report of the tissue biopsy proving it to be a small cell cancer. Immunohistochemistry was positive for CD56, synaptophysin, and pan-cytokeratin. These results confirmed the diagnosis of gastric metastasis of a neuroendocrine small cell carcinoma from the lung.