Open AccessInterleukin-22 ameliorates liver fibrogenesis by attenuating hepatic stellate cell activation and downregulating the levels of inflammatory cytokines
Author(s) -
Donghong Lu,
Xiaoyun Guo,
Shanyu Qin,
Wei Luo,
Xiaoli Huang,
Mei Chen,
Jiaxu Wang,
Shi-Jia Ma,
XianWen Yang,
HaiXing Jiang
Publication year - 2015
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v21.i5.1531
Subject(s) - hepatic stellate cell , interleukin 17 , fibrosis , hepatic fibrosis , medicine , tumor necrosis factor alpha , interleukin , endocrinology , inflammation , cytokine
To investigate the effect of interleukin (IL)-22 on hepatic fibrosis in mice and the possible mechanism involved.