Open AccessHypoxia-inducible factor-1 modulates upregulation of mutT homolog-1 in colorectal cancer
Author(s) -
Yuan Qiu,
Hong Zheng,
Lihua Sun,
Ke Peng,
Weidong Xiao,
Hua Yang
Publication year - 2015
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v21.i48.13447
Subject(s) - blot , downregulation and upregulation , messenger rna , small interfering rna , in vivo , microbiology and biotechnology , colorectal cancer , hypoxia (environmental) , immunohistochemistry , real time polymerase chain reaction , chemistry , cell culture , cancer research , biology , transfection , gene , cancer , immunology , biochemistry , genetics , organic chemistry , oxygen
To investigate the roles and interactions of mutT homolog (MTH)-1 and hypoxia-inducible factor (HIF)-1α in human colorectal cancer (CRC).