Open AccessCurrent stage in inflammatory bowel disease: What is next?
Author(s) -
Gonzalo Jesús Gómez-Gómez
Publication year - 2015
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v21.i40.11282
Subject(s) - inflammatory bowel disease , medicine , pharmacogenetics , disease , intensive care medicine , incidence (geometry) , drug development , crohn's disease , ulcerative colitis , stage (stratigraphy) , inflammatory bowel diseases , drug , pharmacology , genotype , paleontology , biochemistry , chemistry , physics , biology , optics , gene
In recent years, the incidence of inflammatory bowel disease (IBD) has been on the rise, extending to countries where it was infrequent in the past. As a result, the gap between high and low incidence countries is decreasing. The disease, therefore, has an important economic impact on the healthcare system. Advances in recent years in pharmacogenetics and clinical pharmacology have allowed for the development of treatment strategies adjusted to the patient profile. Concurrently, new drugs aimed at inflammatory targets have been developed that may expand future treatment options. This review examines advances in the optimization of existing drug treatments and the development of novel treatment options for IBD.