Open AccessDimethyl sulfoxide inhibits zymosan-induced intestinal inflammation and barrier dysfunction
Author(s) -
Yumeng Li,
Haibin Wang,
Jinguang Zheng,
Xiaodong Bai,
Zengkai Zhao,
Jingyuan Li,
Sen Hu
Publication year - 2015
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v21.i38.10853
Subject(s) - zymosan , myeloperoxidase , malondialdehyde , superoxide dismutase , tunel assay , diamine oxidase , medicine , endocrinology , intestinal mucosa , dimethyl sulfoxide , inflammation , chemistry , tumor necrosis factor alpha , immunology , oxidative stress , pharmacology , apoptosis , biochemistry , enzyme , organic chemistry , in vitro
To investigate whether dimethyl sulfoxide (DMSO) inhibits gut inflammation and barrier dysfunction following zymosan-induced systemic inflammatory response syndrome and multiple organ dysfunction syndrome.