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IGF-1 promotes the growth and metastasis of hepatocellular carcinomaviathe inhibition of proteasome-mediated cathepsin B degradation
Author(s) -
Li Tian,
Lin Xie
Publication year - 2015
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v21.i35.10137
Subject(s) - cancer research , cathepsin b , metastasis , cell growth , biology , cell culture , cathepsin l , cathepsin , cancer , medicine , biochemistry , genetics , enzyme
To investigate the molecular mechanisms of the high IGF-1 level linking diabetes and cancers, which is a risk factor.