Open AccessDual gRNAs guided CRISPR/Cas9 system inhibits hepatitis B virus replication
Author(s) -
Jie Wang,
Zhongwei Xu,
Shuang Liu,
Rui-Yang Zhang,
Shilei Ding,
Xiaodong Xie,
Long Lü,
Xiangmei Chen,
Hui Zhang,
Fengmin Lu
Publication year - 2015
Publication title -
world journal of gastroenterology
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v21.i32.9554
Subject(s) - guide rna , biology , crispr , cccdna , hbsag , hbeag , virology , hepatitis b virus , computational biology , genetics , cas9 , virus , gene
To screen and investigate the effective gRNAs against hepatitis B virus (HBV) of genotypes A-D.