Open AccessMechanisms of pyruvate kinase M2 isoform inhibits cell motility in hepatocellular carcinoma cells
Author(s) -
Yanling Chen,
Jun-Jiao Song,
Xiaochun Chen,
Wei Xu,
Qiang Zhi,
Yunpeng Liu,
Hui Xu,
JinShui Pan,
Jianlin Ren,
Bayasi Guleng
Publication year - 2015
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v21.i30.9093
Subject(s) - pkm2 , cell culture , microbiology and biotechnology , cell growth , biology , cell migration , motility , gene knockdown , reverse transcription polymerase chain reaction , cell , transfection , wound healing , cancer research , pyruvate kinase , gene expression , immunology , glycolysis , biochemistry , gene , genetics , enzyme
To investigate biological mechanisms underlying pyruvate kinase M2 isoform (PKM2) regulation of cell migration and invasion in hepatocellular carcinoma cells.