Open AccessPrimary intestinal lymphangiectasia with generalized warts
Author(s) -
Soon Jae Lee,
Hyun Joo Song,
SunJin Boo,
SooYoung Na,
Heung Up Kim,
Chang Lim Hyun
Publication year - 2015
Publication title -
world journal of gastroenterology
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v21.i27.8467
Subject(s) - lymphangiectasia , medicine , esophagogastroduodenoscopy , hypoalbuminemia , enteropathy , protein losing enteropathy , lymphatic system , chyle , hypogammaglobulinemia , gastroenterology , pathology , immunology , endoscopy , disease , antibody , complication
Primary intestinal lymphangiectasia (PIL) is a rare protein-losing enteropathy with lymphatic leakage into the small intestine. Dilated lymphatics in the small intestinal wall and mesentery are observed in this disease. Laboratory tests of PIL patients revealed hypoalbuminemia, lymphocytopenia, hypogammaglobulinemia and increased stool α-1 antitrypsin clearance. Cell-mediated immunodeficiency is also present in PIL patients because of loss of lymphocytes. As a result, the patients are vulnerable to chronic viral infection and lymphoma. However, cases of PIL with chronic viral infection, such as human papilloma virus-induced warts, are rarely reported. We report a rare case of PIL with generalized warts in a 36-year-old male patient. PIL was diagnosed by capsule endoscopy and colonoscopic biopsy with histological tissue confirmation. Generalized warts were observed on the head, chest, abdomen, back, anus, and upper and lower extremities, including the hands and feet of the patient.