Open AccessDecreased expression of hyperpolarisation-activated cyclic nucleotide-gated channel 3 in Hirschsprung’s disease
Author(s) -
Anne Marie O’Donnell,
David Coyle,
Prem Puri
Publication year - 2015
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v21.i18.5635
Subject(s) - hirschsprung's disease , interstitial cell of cajal , myenteric plexus , hcn channel , immunohistochemistry , enteric nervous system , distal colon , pathology , sigmoid colon , megacolon , medicine , biology , anatomy , ion channel , rectum , disease , receptor
To determine if hyperpolarisation-activated nucleotide-gated (HCN) channels exist in human colon, and to investigate the expression of HCN channels in Hirschsprung's disease.