Open AccessAlterations in serotonin, transient receptor potential channels and protease-activated receptors in rats with irritable bowel syndrome attenuated by Shugan decoction
Author(s) -
Hailian Shi,
Chu-Hsuan Liu,
Lili Ding,
Yu Zheng,
Xiaoyan Fei,
Lu Lu,
Xue-Ming Zhou,
Judy Chia Chun Yuan,
Jing Xie
Publication year - 2015
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v21.i16.4852
Subject(s) - trpv1 , transient receptor potential channel , irritable bowel syndrome , calcitonin gene related peptide , medicine , endocrinology , chemistry , serotonin , capsazepine , receptor , neuropeptide
To determine the molecular mechanisms of Shugan decoction (SGD) in the regulation of colonic motility and visceral hyperalgesia (VHL) in irritable bowel syndrome (IBS).