Open AccessIntestinal genetic inactivation of caspase-8 diminishes migration of enterocytes
Author(s) -
Elke Kaemmerer,
Paula Kuhn,
Ursula Schneider,
Min Hyok Jeon,
Christina Klaus,
Maximilian Schiffer,
Danika Weisner,
Christian Liedtke,
Jörg Jäkel,
Lieven Nils Kennes,
R.-D Hilgers,
Norbert Wagner,
Nikolaus Gaßler
Publication year - 2015
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v21.i15.4499
Subject(s) - enterocyte , biology , microbiology and biotechnology , transgene , genetically modified mouse , crypt , gene knockout , gene knockdown , apoptosis , genetics , gene , small intestine , biochemistry , endocrinology
To verify the hypothesis that caspase-8 (Casp8), which regulates cellular apoptosis and necroptosis, is critically involved in enterocyte migration.