Open AccessIncrease in apoptosis by combination of metformin with silibinin in human colorectal cancer cells
Author(s) -
Cheng-Chia Tsai,
TangWei Chuang,
LiJen Chen,
HoShan Niu,
Kun-Ming Chung,
JueiTang Cheng,
KaoChang Lin
Publication year - 2015
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v21.i14.4169
Subject(s) - silibinin , metformin , apoptosis , viability assay , cancer research , colorectal cancer , tensin , cancer cell , medicine , cancer , pharmacology , biology , pten , pi3k/akt/mtor pathway , biochemistry , insulin
To investigate the effect of metformin on silibinin-induced apoptosis in human colorectal cancer (COLO 205) cells.