Open AccessReactivity against microsatellite instability-induced frameshift mutations in patients with inflammatory bowel disease
Author(s) -
Florian Kuehn,
E. Klar,
Anja Bliemeister,
Michael Linnebacher
Publication year - 2015
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v21.i1.221
Subject(s) - thiopurine methyltransferase , inflammatory bowel disease , immune system , immunology , frameshift mutation , medicine , inflammation , disease , gastroenterology , biology , gene , mutation , genetics
To analyze the cellular immune response towards microsatellite-instability (MSI)-induced frameshift-peptides (FSPs) in patients suffering from inflammatory bowel disease (IBD) with and without thiopurine-based immunosuppressive treatment.