Open AccessZD 7288, an HCN channel blocker, attenuates chronic visceral pain in irritable bowel syndrome-like rats
Author(s) -
Yu Chen,
Chun Lin,
Ying Tang,
Aiqin Chen,
Cuiying Liu,
Dali Lu
Publication year - 2014
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v20.i8.2091
Subject(s) - visceral pain , irritable bowel syndrome , medicine , hcn channel , withdrawal reflex , reflex , anesthesia , hyperalgesia , nociception , chronic pain , threshold of pain , gastroenterology , receptor , ion channel , physical therapy
To investigate the effects of ZD 7288, a hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blocker, on rats with chronic visceral pain.