Open AccessCaspase-12 mediates carbon tetrachloride-induced hepatocyte apoptosis in mice
Author(s) -
Hua Liu,
Zhe Wang,
Michaeł Nowicki
Publication year - 2014
Publication title -
world journal of gastroenterology
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v20.i48.18189
Subject(s) - cytochrome c , carbon tetrachloride , apoptosis , hepatocyte , liver injury , caspase 3 , chemistry , reactive oxygen species , caspase 9 , ccl4 , caspase , microbiology and biotechnology , pharmacology , biochemistry , biology , programmed cell death , organic chemistry , in vitro
To investigate the role of caspase-12 and its downstream targets in carbon tetrachloride (CCl4)-induced hepatocyte apoptosis.