Open AccessSenescent human hepatocytes express a unique secretory phenotype and promote macrophage migration
Author(s) -
Katharine M. Irvine,
Richard Skoien,
Nilesh J. Bokil,
Michelle Melino,
Gethin Thomas,
Dorothy Loo,
Brian Gabrielli,
Michelle M. Hill,
Matthew J. Sweet,
Andrew D. Clouston,
Elizabeth E. Powell
Publication year - 2014
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v20.i47.17851
Subject(s) - senescence , biology , hepatocyte , microbiology and biotechnology , chemokine , hepatocyte growth factor , angiogenin , microarray analysis techniques , gene expression , inflammation , immunology , gene , cancer research , angiogenesis , biochemistry , in vitro , receptor
To develop a model of stress-induced senescence to study the hepatocyte senescence associated secretory phenotype (SASP).