Open AccessAlimentary regimen in non-alcoholic fatty liver disease: Mediterranean diet
Author(s) -
Ludovico Abenavoli,
Nataša Milić,
Valentina Peta,
Francesco Alfieri,
Antonino De Lorenzo,
Stefano Bellentani
Publication year - 2014
Publication title -
world journal of gastroenterology
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v20.i45.16831
Subject(s) - fatty liver , mediterranean diet , medicine , disease , insulin resistance , obesity , type 2 diabetes , management of obesity , regimen , diabetes mellitus , weight loss , endocrinology
Non-alcoholic fatty liver disease (NAFLD) is the most common liver disease worldwide. The mechanisms of the underlying disease development and progression are awaiting clarification. Insulin resistance and obesity-related inflammation status, among other possible genetic, dietary, and lifestyle factors, are thought to play the key role. There is no consensus concerning the pharmacological treatment. However, the dietary nutritional management to achieve weight loss is an essential component of any treatment strategy. On the basis of its components, the literature reports on the effectiveness of the Mediterranean diet in reducing cardiovascular risk and in preventing major chronic diseases, including obesity and diabetes. New evidence supports the idea that the Mediterranean diet, associated with physical activity and cognitive behaviour therapy, may have an important role in the prevention and the treatment of NAFLD.