Open AccessMetformin does not improve survival in patients with hepatocellular carcinoma
Author(s) -
Mamatha Bhat,
Roongruedee Chaiteerakij,
William S. Harmsen,
Cathy D. Schleck,
Ju Dong Yang,
Nasra H. Giama,
Terry M. Therneau,
Gregory J. Gores,
Lewis R. Roberts
Publication year - 2014
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v20.i42.15750
Subject(s) - medicine , metformin , hepatocellular carcinoma , gastroenterology , nonalcoholic fatty liver disease , fatty liver , cohort , diabetes mellitus , retrospective cohort study , hepatitis c , univariate analysis , liver disease , disease , multivariate analysis , endocrinology , insulin
To assess whether metformin, which has a chemopreventive effect in chronic liver disease, has any chemotherapeutic effect in hepatocellular carcinoma.