Open AccessN-acetylcysteine attenuates reactive-oxygen-species-mediated endoplasmic reticulum stress during liver ischemia-reperfusion injury
Author(s) -
Yong Sun,
Liyong Pu,
Ling Lü,
Xuehao Wang,
Feng Zhang,
Jianhua Rao
Publication year - 2014
Publication title -
world journal of gastroenterology
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v20.i41.15289
Subject(s) - unfolded protein response , reactive oxygen species , acetylcysteine , endoplasmic reticulum , reperfusion injury , malondialdehyde , oxidative stress , glutathione , lactate dehydrogenase , chemistry , apoptosis , pharmacology , thapsigargin , chop , superoxide dismutase , liver injury , ischemia , microbiology and biotechnology , biochemistry , medicine , biology , antioxidant , enzyme
To investigate the effects of N-acetylcysteine (NAC) on endoplasmic reticulum (ER) stress and tissue injury during liver ischemia reperfusion injury (IRI).