Open AccessNovel strategies for managing pancreatic cancer
Author(s) -
Welley Siu Loc,
Jill P. Smith,
Gail L. Matters,
Mark Kester,
James H. Adair
Publication year - 2014
Publication title -
world journal of gastroenterology
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v20.i40.14717
Subject(s) - pancreatic cancer , malignancy , medicine , pancreatic intraepithelial neoplasia , cancer , incidence (geometry) , oncology , intensive care medicine , pancreatic ductal adenocarcinoma , physics , optics
With the incidence reports of pancreatic cancer increasing every year, research over the last several decades has been focused on the means to achieve early diagnosis in patients that are at a high risk of developing the malignancy. This review covers current strategies for managing pancreatic cancer and further discusses efforts in understanding the role of early onset symptoms leading to tumor progression. Recent investigations in this discussion include type 3c diabetes, selected biomarkers and pathways related to pancreatic intraepithelial neoplasia lesions, drug resistance, and advances in nanomedicine which may provide significant solutions for improving early detection and treatments in future medicine.