Open AccessLong-term survival after enucleation of a giant esophageal gastrointestinal stromal tumor
Author(s) -
Zhimin Mu,
Yu Xie,
Xuxing Peng,
Hai Zhang,
Gang Hui,
Hao Wu,
Jixian Liu,
Bao-Kun Chen,
Da Wu,
Yiwang Ye
Publication year - 2014
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v20.i37.13632
Subject(s) - medicine , gist , esophagus , stromal tumor , enucleation , thoracotomy , cd117 , radiology , surgery , esophagectomy , physical examination , pathology , stromal cell , cd34 , esophageal cancer , stem cell , cancer , biology , genetics
Gastrointestinal stromal tumors (GISTs) are rare mesenchymal neoplasms of the gastrointestinal tract. Less than 1% occurs in the esophagus. Surgery is the primary treatment for patients with GISTs. We report a 29-year-old male was admitted after the detection of a posterior mediastinal mass during work-up with routine examination. He did not have any disease-related symptoms. The physical examination was unremarkable. Chest computed tomographic scan, the barium esophagogram and endoscopic esophageal ultrasound showed benign neoplasm. The patient was performed an enucleation surgery through the right posterolateral thoracotomy. The pathology revealed a 13.0 cm × 12.0 cm × 5.0 cm mass. The tumor was CD117 (C-kit), PDGFRA and DOG1 positive. These findings were consistent with a GIST of the esophagus. So the diagnosis of GIST of esophagus was confirmed. The pathological diagnosis of low grade of GIST of esophagus was confirmed. The patient has no evidence of recurrence and is in good clinical conditions up-to date, five years after surgery.