Open AccessKISS1methylation and expression as predictors of disease progression in colorectal cancer patients
Author(s) -
Shaoqin Chen,
Zhihua Chen,
Suyong Lin,
Qing Dai,
Liya Fu,
Ruiqing Chen
Publication year - 2014
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v20.i29.10071
Subject(s) - methylation , dna methylation , colorectal cancer , cancer research , biology , metastasis , microbiology and biotechnology , cancer , gene expression , medicine , gene , genetics
To examine the effect of aberrant methylation of the KISS1 promoter on the development of colorectal cancer (CRC) and to investigate reversing aberrant methylation of the KISS1 promoter as a potential therapeutic target.