Open AccessRole of the Na+/K+/2Cl-cotransporter NKCC1 in cell cycle progression in human esophageal squamous cell carcinoma
Author(s) -
Atsushi Shiozaki,
Yoshito Nako,
Daisuke Ichikawa,
Hirotaka Konishi,
Shuhei Komatsu,
Takeshi Kubota,
Hitoshi Fujiwara,
Kazuma Okamoto,
Mitsuo Kishimoto,
Yoshinori Marunaka,
Eigo Otsuji
Publication year - 2014
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v20.i22.6844
Subject(s) - cell cycle , gene knockdown , small interfering rna , cell cycle checkpoint , cancer research , biology , cell , cell growth , microarray analysis techniques , immunohistochemistry , gene expression , microbiology and biotechnology , cell culture , gene , transfection , immunology , biochemistry , genetics
To investigate the role of Na(+)/K(+)/2Cl(-) cotransporter 1 (NKCC1) in the regulation of genes involved in cell cycle progression and the clinicopathological significance of its expression in esophageal squamous cell carcinoma (ESCC).