Open AccessIGFBPrP1 induces liver fibrosis by inducing hepatic stellate cell activation and hepatocyte apoptosisviaSmad2/3 signaling
Author(s) -
Yun Zhang,
Qianqian Zhang,
Xingyi Guo,
Haiyan Zhang,
Lixin Liu
Publication year - 2014
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v20.i21.6523
Subject(s) - hepatic stellate cell , western blot , microbiology and biotechnology , hepatocyte , fibronectin , apoptosis , gene knockdown , biology , fibrosis , chemistry , cell , medicine , endocrinology , in vitro , gene , biochemistry
To investigate the role and mechanism of insulin-like growth factor binding protein-related protein 1 (IGFBPrP1) in the development of liver fibrosis.