Open AccessAn extremely rare case of pancreatic metastasis of esophageal squamous cell carcinoma
Author(s) -
Hiroshi Okamoto,
Yasuyuki Hara,
Masahiro Chin,
Motohisa Hagiwara,
Yuji Onodera,
Shinichiro Horii,
Yasuhiro Shirahata,
Takashi Kamei,
Eiji Hashizume,
Noriaki Ohuchi
Publication year - 2014
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v20.i2.593
Subject(s) - medicine , esophagectomy , chemoradiotherapy , metastasis , standardized uptake value , esophageal cancer , pancreatic cancer , pancreatectomy , esophageal squamous cell carcinoma , chemotherapy , radiology , positron emission tomography , pancreas , carcinoma , oncology , cancer
We report a rare case of a 68-year-old male with metachronous pancreatic metastasis that was resected 2 years after salvage esophagectomy for local recurrence of esophageal squamous cell carcinoma (ESCC). Two years and 8 mo ago, he had undergone definitive chemoradiotherapy for the lower thoracic ESCC and achieved a complete response. Chemoradiotherapy used the protocol of the Japan Clinical Oncology Group trial 9906. Approximately 8 mo later, he developed a local recurrence of the ESCC and underwent thoracoscopic salvage esophagectomy followed by reconstruction with a conduit colon graft via a subcutaneous route. Recently, a tumor of the pancreatic body was found on routine follow-up computed tomography (CT). The tumor diameter was 15 mm on CT, and the maximum standardized uptake value of the lesion was 5.49 at 18F-2-fluoro-2-deoxy-D-glucose positron-emission tomography, strongly suggesting pancreatic cancer. In addition, all tumor markers were within the reference intervals. Therefore, distal pancreatectomy was performed with the resultant histological diagnosis being confirmed as pancreatic metastasis of the ESCC. He was treated with adjuvant chemotherapy, and there has been no evidence of recurrence 9 mo after the surgery. Resection of pancreatic metastasis offers a good prognosis and should be considered for solitary ESCC metastasis.