Open AccessArsenic trioxide induces apoptosis of human gastrointestinal cancer cells
Author(s) -
Zongwen Ma,
Hongyu Xu,
Miao Jiang,
Youlin Yang,
Lianxin Liu,
Yinghua Li
Publication year - 2014
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v20.i18.5505
Subject(s) - gastrointestinal cancer , arsenic trioxide , apoptosis , cancer , medicine , immunohistochemistry , colorectal cancer , terminal deoxynucleotidyl transferase , tunel assay , cancer cell , adenocarcinoma , gastrointestinal epithelium , pathology , gastroenterology , cancer research , gastrointestinal tract , biology , biochemistry
To investigate the changes in apoptosis in gastrointestinal cancer cells from patients with gastrointestinal cancers treated with arsenic trioxide (As₂O₃); and to study the possible molecular mechanisms of such changes by detecting the expression levels of p53 and Bcl-2.