Open AccessThiopurine-methyltransferase variants in inflammatory bowel disease: Prevalence and toxicity in Brazilian patients
Author(s) -
Ana Teresa Pugas Carvalho,
Barbara C. Esberard,
Renata S B Fróes,
Davy Rapozo,
Ana Grinman,
Tatiana de Almeida Simão,
Juliana C. Santos,
Antonio José V. Carneiro,
Luís Felipe Ribeiro Pinto,
Heitor Siffert Pereira de Souza
Publication year - 2014
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v20.i12.3327
Subject(s) - thiopurine methyltransferase , inflammatory bowel disease , genotype , medicine , gastroenterology , azathioprine , ulcerative colitis , neutropenia , disease , immunology , toxicity , biology , gene , genetics
To analyze the prevalence of thiopurine-methyltransferase (TPMT) genotypes and their association with drug toxicity in inflammatory bowel disease (IBD) patients from southeastern Brazil.