Open AccessManagement of intestinal failure in inflammatory bowel disease: Small intestinal transplantation or home parenteral nutrition?
Author(s) -
Elizabeth Harrison,
Philip Allan,
Amrutha Ramu,
Anil Vaidya,
Simon Travis,
Simon Lal
Publication year - 2014
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v20.i12.3153
Subject(s) - parenteral nutrition , medicine , intestinal failure , transplantation , inflammatory bowel disease , intensive care medicine , disease , quality of life (healthcare) , gastroenterology , short bowel syndrome , nursing
Inflammatory bowel disease and Crohn's disease in particular, is a common cause of intestinal failure. Current therapeutic options include home parenteral nutrition and intestinal transplantation. For most patients, home intravenous therapy including parenteral nutrition, with a good probability of long-term survival, is the favoured choice. However, in selected patients, with specific features that may shorten survival or complicate home parenteral nutrition, intestinal transplantation presents a viable alternative. We present survival, complications, quality of life and economic considerations that currently influence individualised decision-making between home parenteral nutrition and intestinal transplantation.