Open AccessATG16L1andNOD2polymorphisms enhance phagocytosis in monocytes of Crohn’s disease patients
Author(s) -
Simone C. Wolfkamp,
C. Verseyden,
Esther Vogels,
Sander Meisner,
Kirsten Boonstra,
Charlotte P. Peters,
Pieter Stokkers,
Anje A. te Velde
Publication year - 2014
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v20.i10.2664
Subject(s) - atg16l1 , phagocytosis , nod2 , immunology , autophagy , crohn's disease , single nucleotide polymorphism , biology , monocyte , inflammatory bowel disease , microbiology and biotechnology , gene , medicine , immune system , disease , genotype , innate immune system , genetics , apoptosis
To investigate if the presence of relevant genetic polymorphisms has effect on the effectual clearance of bacteria by monocytes and granulocytes in patients with Crohn's disease (CD).