Open AccessSchistosoma japonicum egg antigen up-regulates fibrogenesis and inhibits proliferation in primary hepatic stellate cells in a concentration-dependent manner
Author(s) -
Ping Liu,
Mi Wang,
Xiaodan Lü,
Shujuan Zhang,
WangXian Tang
Publication year - 2013
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v19.i8.1230
Subject(s) - schistosoma japonicum , hepatic stellate cell , microbiology and biotechnology , biology , antigen , blot , protein kinase b , western blot , hepatic fibrosis , signal transduction , fibrosis , immunology , schistosomiasis , biochemistry , endocrinology , pathology , medicine , helminths , gene
To investigate the effects of different concentrations of Schistosoma japonicum (S. japonicum) egg antigen on fibrogenesis and apoptosis in primary hepatic stellate cells (HSCs).