Open AccessLong interspersed nuclear element ORF-1 protein promotes proliferation and resistance to chemotherapy in hepatocellular carcinoma
Author(s) -
Fan Feng,
Yinying Lu,
Fan Zhang,
Xudong Gao,
Chuanfu Zhang,
Alex Meredith,
Zhongxian Xu,
Yutao Yang,
Xiujuan Chang,
Hong Wang,
Jing Qu,
Zhen Zeng,
Jing Yang,
Chunping Wang,
Yaping Zhu,
Jiahuan Cui,
Yongping Yang
Publication year - 2013
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v19.i7.1068
Subject(s) - epirubicin , cisplatin , cell culture , cell growth , apoptosis , biology , microbiology and biotechnology , flow cytometry , doxorubicin , cancer research , mtt assay , paclitaxel , chemotherapy , biochemistry , genetics , cyclophosphamide
To clarify the specific roles and mechanisms of long interspersed nuclear element-1 ORF-1 protein [human long interspersed nuclear element-1 (LINE-1), ORF-1p] in chemotherapeutic drug resistance and cell proliferation regulation in hepatocellular carcinoma (HCC) cells.