Open AccessAnti-miRNA-221 sensitizes human colorectal carcinoma cells to radiation by upregulating PTEN
Author(s) -
Qi Xue,
Kai Sun,
Haijun Deng,
Shangtong Lei,
Jinqiao Dong,
Guoxin Li
Publication year - 2013
Publication title -
world journal of gastroenterology
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v19.i48.9307
Subject(s) - tensin , pten , microbiology and biotechnology , transfection , cell culture , lipofectamine , luciferase , microrna , biology , flow cytometry , chemistry , cancer research , gene , signal transduction , pi3k/akt/mtor pathway , recombinant dna , biochemistry , genetics , vector (molecular biology)
To investigate the regulative effect of miRNA (miR)-221 on colorectal carcinoma (CRC) cell radiosensitivity and the underlying mechanisms.