
Insulin-like growth factor-1 induces lymphangiogenesis and facilitates lymphatic metastasis in colorectal cancer
Author(s) -
Zhenjun Li,
Xiaojiang Ying,
Hongliang Chen,
Pingjiang Ye,
Zhiliang Chen,
Gang Li,
Hongyi Jiang,
Jiang Liu,
Shiyue Zhou
Publication year - 2013
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v19.i43.7788
Subject(s) - lymphangiogenesis , lymphatic vessel , lymphatic system , metastasis , cancer research , colorectal cancer , immunohistochemistry , medicine , growth factor , cancer , vascular endothelial growth factor c , insulin like growth factor , pathology , receptor , vascular endothelial growth factor , vascular endothelial growth factor a , vegf receptors
To investigate the expression of insulin-like growth factor-1 (IGF-1)/insulin-like growth factor-1 receptor (IGF-1R) in colorectal cancer (CRC) tissues and to analyze their correlation with lymphangiogenesis and lymphatic metastasis.