Open Access8-bromo-7-methoxychrysin inhibits properties of liver cancer stem cellsviadownregulation of β-catenin
Author(s) -
Meifang Quan,
Li Xiao,
Zhihong Liu,
Hui Guo,
Kai Ren,
Fei Liu,
Ji Cao,
Xiyun Deng
Publication year - 2013
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v19.i43.7680
Subject(s) - stem cell , cancer stem cell , cancer research , stem cell marker , cell culture , carcinogenesis , catenin , biology , in vivo , lgr5 , cell sorting , microbiology and biotechnology , chemistry , cancer , wnt signaling pathway , signal transduction , flow cytometry , genetics
To evaluate whether 8-bromo-7-methoxychrysin (BrMC), a synthetic analogue of chrysin, inhibits the properties of cancer stem cells derived from the human liver cancer MHCC97 cell line and to determine the potential mechanisms.