Open AccessCurcumin cytotoxicity is enhanced by PTEN disruption in colorectal cancer cells
Author(s) -
Lin Chen,
Wenfeng Li,
Hong-Xiao Wang,
Hanqing Zhao,
Junhua Tang,
Changjie Wu,
Lijuan Lu,
Wanqin Liao,
Xincheng Lu
Publication year - 2013
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v19.i40.6814
Subject(s) - pten , cancer research , clonogenic assay , cell cycle , curcumin , tensin , cytotoxicity , cancer cell , apoptosis , biology , cell cycle checkpoint , cell growth , chemistry , microbiology and biotechnology , cancer , pharmacology , pi3k/akt/mtor pathway , biochemistry , genetics , in vitro
To investigate the effects of phosphatase and tensin homolog deleted on chromosome 10 (PTEN) deficiency on the cytotoxicity of chemotherapeutic agents toward colorectal cancer cells.