Open AccessCdx2 expression and its promoter methylation during metaplasia-dysplasia-carcinoma sequence in Barrett's esophagus
Author(s) -
Kenji Makita,
Riko Kitazawa,
Shuho Semba,
Koto Fujiishi,
Miku Nakagawa,
Ryuma Haraguchi,
Sohei Kitazawa
Publication year - 2013
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v19.i4.536
Subject(s) - cdx2 , intestinal metaplasia , dysplasia , methylation , dna methylation , biology , adenocarcinoma , pathology , immunohistochemistry , esophagus , metaplasia , cancer research , medicine , cancer , gene expression , gene , anatomy , genetics , homeobox
To examine how the expression of caudal type homebox transcription factor 2 (Cdx2) is regulated in the development of malignancy in Barrett's esophagus.