Open AccessCytokeratin 8 is increased in hepatitis C virus cells and its ectopic expression induces apoptosis of SMMC7721 cells
Author(s) -
Mingzhu Sun
Publication year - 2013
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v19.i37.6178
Subject(s) - transfection , microbiology and biotechnology , blot , cytokeratin , clone (java method) , biology , cell culture , ectopic expression , hepatitis c virus , virology , real time polymerase chain reaction , western blot , apoptosis , expression vector , reverse transcription polymerase chain reaction , cell , messenger rna , virus , gene , recombinant dna , immunohistochemistry , immunology , genetics
To investigate cytokeratin 8 (CK8) overexpression during hepatitis C virus (HCV) infection and its pathogenesis, and the effect of ectopic CK8 expression on hepatoma cell lines.