Open AccessMetachronous intracystic and intraductal papillary neoplasms of the biliary tree
Author(s) -
Hirotoshi Sato,
Yasunori Sato,
Kenichi Harada,
Motoko Sasaki,
Katsuyasu Hirano,
Yasuni Nakanuma
Publication year - 2013
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v19.i36.6125
Subject(s) - gallbladder , cholecystectomy , medicine , bile duct , carcinoma , papillary tumor , pathology , intraductal papillary mucinous neoplasm , gastroenterology , pancreas
A 77-year-old woman complained of epigastralgia, and a tumor (5 cm in diameter) of the gallbladder neck was detected by image analysis. Following cholecystectomy, the tumor was pathologically diagnosed as intraductal papillary neoplasm (IPN), gastric type, with associated invasive carcinoma. About 10 mo later, intraluminal multiple masses (3 foci, up to 1.8 cm) were noted in the extrahepatic bile duct, and the resected specimen showed that all tumors had similar gross and microscopic features as seen in gallbladder IPN without invasion, and they were synchronous multiple lesions. This case showed a papillary tumor of the gallbladder of gastric phenotype, and confirmed that the gallbladder is a target of IPN in addition to the bile ducts.