Open AccessAberrant TGF-β1 signaling contributes to the development of primary biliary cirrhosis in murine model
Author(s) -
Bin Liu,
Xuan Zhang,
Fengchun Zhang,
Jin-bao Zong,
Wen Zhang,
Yan Zhao
Publication year - 2013
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v19.i35.5828
Subject(s) - primary biliary cirrhosis , foxp3 , medicine , endocrinology , alkaline phosphatase , flow cytometry , pathogenesis , il 2 receptor , transforming growth factor , receptor , biology , chemistry , microbiology and biotechnology , immunology , immune system , t cell , biochemistry , enzyme
To investigate whether transforming growth factor-β1 (TGF-β1) signaling pathway is involved in the pathogenesis of primary biliary cirrhosis (PBC).